Finished the book. Review in progress, somewhere between zero and infinity. Each chapter begins with a quote to set the tone. Here is my favorite:

“When you can measure what you are speaking about, and express it in numbers, you know something about it; but when you cannot measure it, when you cannot express it in numbers, your knowledge is of a meager and unsatisfactory kind: it may be the beginning of knowledge, but you have scarely, in your thoughts, advanced to the stage of science. “

- William Thomson, Lord Kelvin

This is largely the problem traditional HPC sciences have with Life Sciences. Apart from statistical analysis, we simply haven’t risen to the level where we can express biological systems numerically.

(See also: amazon: Zero: The Biography of a Dangerous Idea)
(See also: wikipedia: Charles Seife)
(See also: Charles Seife)

(See also: amazon: The Nothing that Is: A Natural History of Zero, by Robert Kaplan)